Shorter-term and longer-term mortality prediction in the Australian Diabetes, Obesity and Lifestyle (AusDiab) study

Abstract

Background: While identification of key risk factors for mortality has contributed to advances in healthcare, the effect of these risk factors in predicting mortality over different time horizons remains unclear. Aims: We sought to determine how risk factors predicted shorter-term and longer-term mortality across the age spectrum in adults. Methods: We used data from 11 247 adults of the Australian Diabetes, Obesity and Lifestyle (AusDiab) study. Cox multivariable regression models were used to estimate hazard ratios (HRs) of shorter-term (0–10 years) and longer-term (10–20 years) all-cause and cardiovascular disease (CVD)-related mortality associated with risk factors. Models with interacti..